Influence of different water types on natural immune response in broiler chickens
Tsvetoslav Koynarski
, Mitko Lalev
, Pavlina Hristakieva
, Nadya Mincheva
, Magdalena Oblakova
, Ivelina Ivanova
Abstract: Current research investigates the impact of various water treatments on immune parameters in broiler chickens, with a focus on the alternative pathway of complement activation (APCA), beta-lysine activity, and serum lysozyme levels. Broilers were subjected to treatments with alkaline, hydrogen, magnetic, and reverse osmosis waters, and immune parameters were assessed. Results revealed that alkaline water treatment elicited the highest APCA activity, followed closely by hydrogen water treatment. Beta-lysine activity was notably enhanced in broilers treated with alkaline and hydrogen waters, while magnetic water treatment showed minimal effects. Additionally, serum lysozyme levels were significantly elevated in birds treated with alkaline water. These findings underscore the potential of water quality interventions, particularly alkaline and hydrogen waters, in enhancing immune function in broiler chickens. This study contributes valuable insights into the role of water treatments in promoting immune health and productivity in poultry farming practices.
Keywords: Beta-lysine activity; broiler chickens; complement system; drinking water; immune response; lysozyme
Citation: Koynarski, Ts., Lalev, M., Hristakieva, P., Mincheva, N., Oblakova, M. & Ivanova, I. (2025). Influence of different water types on natural immune response in broiler chickens. Bulg. J. Agric. Sci., 31(6), 1179–1186
| References: (click to open/close) | Bakshi, J. & Srinivasan, T. M. (2019). A review of the effect of magnetic fields on biological systems: Immune system response. International Journal of Environmental Research and Public Health, 16(19), 1 - 19.
Bozakova, N., Sotirov, L., Koynarski, T. & Gundasheva, D. (2018). Effect of Immunomodulator “Immunobeta” on Humoral Innate and Acquired Immune Response in Layer Hens. Pakistan Veterinary Journal, 38(4), 438 - 441. https://doi.org/10.1097/QCO.0b013e3283638104.
Brown, S. A., White, C. L. & Black, R. J. (2020). Effects of dietary antioxidants on immune responses in broiler chickens. Journal of Applied Poultry Research, 29(4), 947 - 954.
Chen, Y., Hu, S., Zheng, Y., Zhu, J., Lu, L., Li, X. & Zhang, L. (2019). Effects of dietary probiotic supplementation on growth performance, intestinal morphology, and immune parameters in broiler chickens. Poultry Science, 98(4), 1801 - 1809.
Denev, S., Sotirov, L., Chobanova, S., Koynarski, T., Bozakova, N. & Stoev, S. (2020). Effect of silymarin and ochratoxin A on humoral natural immunity of broiler chickens. Journal of Central European Agriculture, 21(3), 492 - 498.
Johnson, L. A., Smith, R. E., Brown, K. R. & Taylor, A. M. (2019). Effects of environmental enrichment on immune parameters in broiler chickens. Animal Welfare, 28(2), 183 - 192.
Johnson, A., Smith, C., Jones, E. & Williams, J. (2019). Effects of dietary probiotic supplementation on immune parameters in broiler chickens. Poultry Science, 98(5), 2101 - 2108.
Karakolev, R., Petrova-Tsenin, P., Petrova, R. & Koynarski, T. (2022). Effect of “Avigen” Immunomodulator on Beta-lysine Activity in Broilers. Yuzuncu Yil University Journal of Agricultural Sciences, 32(2), 260-265
Karakolev, R. & Nikolov, D. (2015). Fluctuations in serum beta-lysine activity in laying hens depending on age, hybrid affiliation and rearing. Poultryfarming, 3, 18 - 19.
Lee, K. W., Lillehoj, H. S., Jang, S. I., Lee, S. H. & Siragusa, G. R. (2010). Direct-fed microbials and their impact on the intestinal microflora and immune system of chickens. Journal of Poultry Science, 47(2), 106 - 114.
Li, Y., Yao, H., Li, J., Zhang, X., Zhang, J., Zhao, Z. & Wu, R. (2012). Effects of magnetic water treatment on immune function of mice. Journal of Animal and Veterinary Advances, 11(6), 735 - 740.
Ohta, S. (2012). Molecular hydrogen is a novel antioxidant to efficiently reduce oxidative stress with potential for the improvement of mitochondrial diseases. Biochimica et Biophysica Acta (BBA) - General Subjects, 1820(5), 586 - 594.
Ostojic, S. M. & Stojanovic, M. D. (2013). Hydrogen-rich water affected blood alkalinity in physically active men. Research in Sports Medicine, 21(3), 244 - 252.
Ordinance 9/2001. (2001).https://lex.bg/laws/ldoc/-549175806.
Peng, Q., Zou, X. T. & Wang, Y. X. (2017). Influence of dietary β-defensin peptides on broiler performance, nutrient digestibility, and serum biochemical parameters. Poultry Science, 96(12), 4374 - 4379.
Schaffner, T., Mueller, S. M. & Markovic, B. B. (2015). The pH balance in infection and inflammation. Infection, 43(4), 381 - 388.
Smith, A. B., Jones, C. D., Johnson, E. K. & Williams, J. M. (2018). Effects of dietary probiotic supplementation on immune function in broiler chickens. Poultry Science, 97(5), 1663 - 1670.
Smith, B., White, D., Black, R. & Taylor, A. (2020). Effects of environmental enrichment on immune parameters in broiler chickens. Animal Welfare, 29(3), 321 - 328.
Sotirov, L., Denev, S., Chobanova, S., Bozakova, N., Velichkova, К., Dinev, T. & Koynarski, T. (2021). Effects of dietary marine microalgae Schizochytrium limacinum on natural humoral immunity of broiler chickens. Bulg. J. Agric. Sci., 27(1), 194 - 199.
Sotirov, L., Koynarski, Ts., Semerdjiev, V., Dimov, D., Laleva, S., Slavova, P., Iliev, M. & Yarkov, D. (2011). Effect of breed upon blood lysozyme and complement activity in different sheep breeds. Agricultural Science and Technology, 3(4), 302 - 305.
Wang, X., Li, P., Sun, G., Liu, J., Zhang, R., Wang, C. & Liu, W. (2017). Effects of dietary supplementation with essential oils on immune parameters and gut morphology in broiler chickens. Journal of Animal Science, 95(12), 5311 - 5323.
Wei, W., Wei, X. & Wu, H. (2008). The effect of low-frequency electromagnetic field on human immune function. Chinese Journal of Immunology, 24(5), 449 - 451.
World Health Organization. (2017). Guidelines for Drinking-water Quality: Fourth Edition Incorporating the First Addendum (Vol. 1). World Health Organization.
Wynn, E., Krieg, M. A., Aeschlimann, J. M. & Burckhardt, P. (2009). Alkaline mineral water lowers bone resorption even in calcium sufficiency: alkaline mineral water and bone metabolism. Bone, 44(1), 120 - 124.
Xu, Y., Xie, C., Zhang, B., Luo, Y. & Huang, Z. (2018). Effects of different levels of dietary lysine on growth performance, intestinal digestion and absorption capacity and antioxidant capacity in broilers. Poultry Science, 97(12), 4331 - 4338. |
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| Date published: 2025-12-16
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