Studies on insecticidal activities of 2-Benzylthio-5-(4-Aminophenyl)-1,3,4-oxadiazole against Helicoverpa armigera
S. М. Turaeva
, D. S. Ismailova
, Sh. Sh. Khasanov
, P. А. Nurmakhmadova
, B. Zh. Elmuradov
, Sh. S. Azimova
, D. Т. Juraev
Abstract: Insecticidal activity of the 2-Benzylthio-5-(4-Aminophenyl)-1,3,4-oxadiazole (2-BAO) against the global crop pest - Helicoverpa armigera was studied in laboratory and field, and the toxicity (LD50) of the substance was evaluated against larva H. armigera, as well as evaluate the effectiveness against H. armigera.
This study aimed to determine the insecticidal activity of 2-Benzylthio-5-(4-Aminophenyl)-1,3,4-oxadiazole (2-BAO) against larvae H. armigera in vivo and in vitro. Evaluate biological effectiveness in the control of H. armigera in fields of the Tashkent region.
For the first time, it was found that the derived 1,3,4-oxadiazoles at 0.1 mg/mL caused 65.5% mortality of cotton bollworm (H. armigera) after 24 h of incubation. The mortality of larvae after 48-hour incubation reached 79.9%. The toxicity of 2-BAO against larvae after 24 h was LC50 0.36 mg/mL.
The insecticidal activity of the 1,3,4-oxadiazole derivative was studied for the first time in vitro against Helicopvera zea, Spodoptera frugiperda, and Trichoplusiya ni insect cells. The results obtained confirm that 2-Benzylthio-5-(4-Aminophenyl)-1,3,4-oxadiazole at a dose of 10 µM/mL exhibits toxicity against cells of various cutworm species, which is confirmed in the experiment in vivo.
The results of field trials showed that on the 7th day, the effectiveness of the substance at a rate of 0.2 kg/ha against larvae H. armigera was 56.0% compared to the control, 11.0% more compared to the insecticide BI-58 (a.i. dimethoate). The effectiveness of 2-Benzylthio-5-(4-Aminophenyl)-1,3,4-oxadiazole (2-BAO) on the 21st day reached 68.5% compared to the control.
These findings suggest that it can be assumed that 2-Benzylthio-5-(4-Aminophenyl)-1,3,4-oxadiazole (2-BAO) can control the number of larvae of pests with the best control efficiency of more than 68.5% when the increasing pest population from reaching the economic injury level.
Keywords: 1,3,4-oxadiazole; effectiveness; Helicoverpa armigera; in vitro; in vivo; insecticidal activity
Citation: Turaeva, S. М., Ismailova, D. S. , Khasanov, Sh. Sh., Nurmakhmadova, P. А., Elmuradov, B. Zh., Azimova, Sh. S. & Juraev, D. Т. (2024). Studies on insecticidal activities of 2-Benzylthio-5-(4-Aminophenyl)-1,3,4-oxadiazole against Helicoverpa armigera. Bulg. J. Agric. Sci.,30(6), 1059–1066
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| Date published: 2024-12-16
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